American Board of Internal Medicine (ABIM) Certification Practice Exam

In which demographic does Type I autoimmune pancreatitis typically present?

1. Older women

2. Older men

3. Young adults

4. Children

The correct answer is: Older men

Type I autoimmune pancreatitis generally presents predominantly in older men, typically ranging from the age of 50 to 70. This demographic is characterized by the presence of other autoimmune conditions, such as primary sclerosing cholangitis or Sjögren's syndrome, which are more prevalent in males. This type of pancreatitis, also known as IgG4-related pancreatitis, features specific immunological markers and responds well to corticosteroid treatment. Understanding the typical presentation in older men helps in distinguishing Type I autoimmune pancreatitis from other types, such as Type II, which can affect a broader age range and is not typically associated with the same immune-related conditions. Recognizing these demographic factors is crucial for healthcare professionals in order to make accurate diagnoses and tailor appropriate treatment strategies.