American Board of Internal Medicine (ABIM) Certification Practice Exam

At what age of breast cancer diagnosis is genetic testing recommended?

1. Above 60 years

2. Before the age of 50 years

3. At any age

4. After 40 years

The correct answer is: Before the age of 50 years

Genetic testing for breast cancer is particularly recommended for individuals diagnosed before the age of 50 due to the higher likelihood of hereditary factors contributing to the cancer's development at a younger age. Early onset of breast cancer can indicate potential mutations in genes such as BRCA1 and BRCA2, which significantly increase the risk of developing breast and other cancers. Individuals diagnosed with breast cancer under 50 may benefit from genetic evaluation to assist in treatment decisions and to inform family members about their potential risk for hereditary cancer. The identification of such genetic mutations can enable proactive surveillance and prevention strategies for both the patient and their relatives. While breast cancer can occur at any age, including in those older than 60, the recommendation to pursue genetic testing in younger patients is based on research that has established a stronger correlation between early diagnosis and genetic predisposition. This timing is crucial for implementing tailored management plans and preventive measures for patients and their families.